One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs ...

A review article led by researchers from the B·ARGO group at the Germans Trias i Pujol Research Institute (IGTP) and from the ...

Researchers created a new kind of cancer drug that can grab a mutant protein while also carrying a second hit against the ...

Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken from normal-appearing skin, including areas usually protected from sunlight.

The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...

Every cancer carries a unique genetic fingerprint: variations in DNA known as “somatic variants” that occur in tumor DNA but are absent from the patient’s healthy cells. While some cancers may also ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval. According to the National Cancer ...

Researchers at the University of Oslo and Oslo University Hospital have developed a promising new immunotherapy targeting the CTNNB1 gene mutation associated with various aggressive cancers like lung ...

UV (ultraviolet) radiation is the primary risk factor of skin cancer, including melanoma. And while most cases are tied to the UV exposure we get from the Sun, tanning beds pose a clear risk as well.