Women who developed severe intrahepatic cholestasis of pregnancy (ICP) after 28 weeks faced over a threefold higher risk of ...

Intrahepatic cholestasis of pregnancy is a gestation-specific liver disorder characterised primarily by pruritus and elevated serum bile acid levels, typically manifesting in the second or third ...

Pregnant patients should discontinue use of thiopurines if they develop intrahepatic cholestasis of pregnancy. The use of thiopurines (eg, azathioprine, 6-mercaptopurine, and 6-thioguanine) by ...

A 41-year-old gravida 5 para 2113 at 32 and 4/7 weeks' gestation presented to labor and delivery with generalized pruritus of 3-days' duration. She had no outward signs of rash or pustules. She also ...

Please provide your email address to receive an email when new articles are posted on . The FDA has issued a safety alert warning patients and health care providers of a “rare risk of intrahepatic ...

In women with intrahepatic cholestasis of pregnancy (ICP), higher peak bile acid levels and elevated maternal BMI (24.6) were associated with an increased risk for pruritus severity deterioration as ...

"Pregnant patients should stop using thiopurines if they develop ICP," the agency stated. ICP impairs the normal release of bile and often manifests as intense itching on the hands and feet. It can ...