Methamphetamine addiction has long been framed as a story of dopamine gone haywire, with the drug flooding the brain’s reward ...

Researchers identified a key molecule that highlights how the immune system is linked to the release of dopamine.

Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While clinical observations suggest that social rank plays a crucial role in determining ...

Neuroscientists find that two distinct neural pathways are responsible for the addictive properties of the opioid fentanyl: one mediates reward, the other promotes the seeking of relief from symptoms ...

For the first time, dopamine regulation has been mapped in real time, deep inside the brains of three humans, revealing how the brain neurotransmitter plays an essential role in not just recognizing ...

Social rank regulates methamphetamine-seeking behavior by modulating the mesocortical and mesolimbic dopamine pathways, and winning experiences can remodel these circuits to suppress drug-seeking. In ...