Spatial microsimulation and population synthesis are pivotal methodologies for constructing detailed, synthetic representations of entire populations at the micro-level. These techniques merge ...

Outcomes including local recurrence, distant metastases, and survival as well as toxicity data were modeled by a patient-level Markov microsimulation model, which were validated against trial data.

Adjuvant therapy in patients with ductal carcinoma in situ who undergo partial mastectomy remains controversial, particularly for low-risk patients (60 years or older, estrogen-positive, tumor extent ...