For Week 18 NFL betting, SportsLine AI has evaluated the NFL odds and provided NFL betting picks for all 16 games. You can only see the AI predictions for the Week 18 NFL schedule here. After analyzing every game in Week 18, the AI says the Rams (-7.5, 46.5), who have already clinched a postseason berth, cover comfortably against the Cardinals.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the Detroit Lions and Chicago Bears.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for Sunday football game between Washington Commanders, Philadelphia Eagles.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

We've reached the final week of the regular season. Here's an early look at some predictions and picks for the 2026 NFL playoffs.

NFL Week 18 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the New York Jets and Buffalo Bills.

The SportsLine Projection Model has revealed its Tampa Bay vs. Carolina picks for the NFL Week 18 matchup on Saturday

A Baltimore Ravens and Pittsburgh Steelers clash will be among several Week 18 season-finale matchups featuring major NFL playoff implications.