Microfluidic Sanger sequencing is the implementation of the Sanger method of DNA sequencing on a chip; therefore, this allows for the manipulation of fluids at the submicron size. Requiring much ...

DNA sequencing has a remarkable history, in terms of inception and evolution of the technologies themselves, as well as the breadth and scope of problems to which they have been applied. This Nature ...

Patterns of care in adjuvant systemic therapy of patients with stage III melanoma: A U.S. population-based study.

At the age of 4, Nicholas Volker seemed to be dying. There was something seriously wrong with his gut but no one could figure out what. In desperation, doctors sequenced his genome – and not only ...

Frederick Sanger, a British biochemist whose discoveries about the chemistry of life led to the decoding of the human genome and earned him two Nobel Prizes, a distinction held by only three other ...

Genome assembly, the molecular equivalent of trying to put together a multi-million piece jigsaw puzzle without knowing what the picture on the cover of the box is, remains challenging due to the very ...

When DNA sequencing first broke onto the scene in the 1970s, one method shone brighter than even Sanger sequencing. However, this method is now almost obsolete. What was it and what happened to it? In ...

DNA sequencing has undergone radical advances since the first Sanger sequencing method was introduced in 1977. Sanger sequencing made use of randomly added chain-terminating deoxynucleotides during ...