The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage ...
Next Gen Stats Insight for 49ers-Colts (via NFL Pro): Brock Purdy has a 144.6 passer rating when targeting George Kittle this season, the highest between any QB-receiver duo in the last five seasons ...
The Indianapolis Colts will look to snap a four-game losing streak when they battle the San Francisco 49ers on Monday Night Football. San Francisco is coming off a 37-24 win over the Tennessee Titans ...
The last chance to make a Week 16 NFL SGP comes on 'Monday Night Football' as the San Francisco 49ers visit the Indianapolis Colts (4.5, 46.5) at 8:15 p.m. ET. Both teams are on streaks, as San Fran ...
Philip Rivers will start once again for the Indianapolis Colts when the team faces the San Francisco 49ers in the Week 16 edition of Monday Night Football. The 8-6 Colts will host the 10-4 49ers at ...
Brock Purdy and the San Francisco 49ers visit Philip Rivers and the Indianapolis Colts on Monday Night Football to close out Week 16 of the 2025 NFL season. The Niners defeated the Tennessee Titans 37 ...
The San Francisco 49ers will play the Indianapolis Colts for Monday Night Football. The Week 16 game is scheduled for 8:15 p.m. on Monday, Dec. 22, 2025. Viewers can watch the game on ESPN or stream ...
The San Francisco 49ers will visit the Indianapolis Colts for Monday Night Football. This Week 16 game is scheduled for Monday, December 22, 2025, at 8:15 p.m. The matchup will be broadcast on ESPN ...
The Indianapolis Colts were once the top team in the AFC in the early stages of the 2025 NFL season. Now, the team is fighting just for a chance to get into the playoff race. The Colts have dropped ...
Who will win on Monday Night Football in NFL Week 16? The Arizona Republic is predicting a 20-17 win for the 49ers over the Colts in the NFL Week 16 Monday Night Football game. Jeremy Cluff writes: ...
The San Francisco 49ers will play the Indianapolis Colts for Monday Night Football. The Week 16 game is scheduled for Monday, Dec. 22, 2025, at 8:15 p.m. Viewers can watch the game on ESPN or stream ...
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