Understand the replacement chain method, a crucial capital budgeting tool for comparing projects with different life spans. Explore how it works, its requirements, and alternatives.

Pharmaceutical Separation Science Session Day two of HPLC 2025 concluded with a session on pharmaceutical separations chaired ...

White analytical chemistry (WAC) integrates environmental, performance, and economic factors in method evaluation, aligning with green chemistry principles. The Red Analytical Performance Index (RAPI) ...

Validation of an analytical method provides evidence that when correctly applied, it produces results that are fit for purpose, thereby demonstrating the effectiveness of the method with an acceptable ...

Laboratory-based design verification testing (DVT) of combination products and medical devices must be performed to demonstrate that the device meets the performance requirements that were set in the ...

A novel HPLC method was developed and validated for the determination of D-Carnitine in Levocarnitine in accordance with the ICH Q2R1 guidelines. The method demonstrated system precision, specificity, ...

Size-exclusion chromatography (SEC) is a leading method for analyzing size variants by separating high molecular weight and low molecular weight species from the monomer based on their hydrodynamic ...

The administration of this test is an essential element in the process of method development, as it guarantees the capability of the LC equipment and the established technique to deliver reliable ...

Background: Pralsetinib, a targeted inhibitor of the RET enzyme, plays a critical role in the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) ...

Introduction: Polymyxin B is widely used to treat infections caused by multidrug-resistant Gram-negative bacteria. However, the pharmacokinetic study data of PB in the elderly are scarce. Herein, a ...