This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Binding of aminoglycoside antibiotics to 16S ribosomal RNA induces a particular structure of the decoding center and increases the misincorporation of near-cognate amino acids. By kinetic analysis we ...

As avid puzzlers know full well, the humble jigsaw puzzle is a thing of beauty in multiple ways. Not only are jigsaws an absorbing time sink, but multiple studies have demonstrated they are good for ...