ULYSSES is a highly innovative Horizon Europe Pathfinder project aimed at developing a next-generation, yeast-based biosensor for the early detection of breast and prostate cancer through urine ...

Vasoactive Intestinal Peptide (VIP) has remained a molecule of considerable scientific interest since its initial characterization as a 28–amino acid neuropeptide with widespread distribution ...

This article and associated images are based on a poster originally authored by Sam Hoare, Luciana Leo, Anastasia Schultz, and Thom Hughes and presented at ELRIG Drug Discovery 2025 in affiliation ...

The cryptocurrency market crash took a drastic turn as the total market cap dropped to $3.13 trillion on Nov. 20. Bitcoin (BTC) crashed below the $87,000 price mark, down 2.45% in the last 24 hours.

New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, ...

About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane receptors called G protein-coupled receptors (GPCRs). GPCRs are indispensable for ...

Understanding what causes a compound to be a biased modulator is a key step in enabling the design of compounds with more precision in the array of G proteins that they activate. The scientists ...

This important study fills a gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...

A newly discovered receptor switch that boosts bone growth could transform how we treat osteoporosis, by stimulating the body’s own bone-building machinery using a targeted drug and even mechanical ...

State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, ...

The GPCR-targeting therapies market is expected to grow significantly in the coming years. This is due to the increasing number of patients who are being diagnosed with cancer, the growing awareness ...