Abstract: This paper investigates the application of the gradient descent method in moving horizon state estimation for discrete-time nonlinear systems with line-search optimization based on a reduce ...

Discover how early CMC, process optimization, and formulation strategy drive scalable, commercially viable drugs.

Abstract: This paper presents an extended gradient-based optimization framework for optimal control problems governed by general conformable fractional derivatives (GCFDs), which unify various ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

WASHINGTON — A new report from the National Academies of Sciences, Engineering, and Medicine examines how the U.S. Department of Energy could use foundation models for scientific research, and finds ...