Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already ...

Scientists mapped where drugs bind inside the body, cell by cell, to better understand benefits and side effects.

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

As women age, protein becomes crucial for healthy muscle, bones and metabolism. Getting at least 1–1.2 grams per kilogram body weight per day is a good goal, but needs may go up to 1.6 g/kg/day. In ...

Background: Neuromuscular blocking agents (NMBAs) may induce life-threatening perioperative hypersensitivity reactions (POH). In addition to the known IgE-dependent allergic background, a mechanism ...

Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with annotated experimental binding potency data. According to the company, the ...

Kanishma Ray is a writer at GameRant, who's known to play a mean violin (decently, that is). She's a Computer Science student by day and a wordsmith by night, with a knack for crafting engaging and ...

Abstract: Predicting protein-ligand binding affinities is a critical problem in drug discovery and design. A majority of existing methods fail to accurately characterize and exploit the geometrically ...

Abstract: The success of drug discovery relies on predicting the binding affinity of protein-ligand. Applying deep learning to this field can expedite the process and reduce resource consumption.